Sania Mirza's challenge at the Kremlin Cup in Moscow ended after she bowed out of the doubles event as well on Thursday.
The Indian ace and her Swiss partner Patty Schnyder failed to make the most of opportunities and went down 3-6, 7-5, 7-10 to Cara Black of Zimbabwe and Liezel Huber of the United States in the quarter-finals.
Black-Huber saved nine of the 12 break points they faced in the one hour 33-minute contest to snatch a semi-final berth.
Sania had lost 3-6, 4-6 to Argentina's Gisela Dulko in the singles first round.
In Vienna, second seeds Leander Paes and Martin Damm face the American pair of Mardy Fish and Robby Ginepri in the quarter-finals on Thursday.
The Indo-Czech duo defeated Argentina's Agustin Calleri and Italy's Andreas Seppi 4-6, 6-2, 10-7 in the first round.
