Holders Atletico Madrid won for the first time in the Europa League this season, beating Rosenborg 3-0, while Emmanuel Adebayor scored a hat-trick as Manchester City beat Lech Poznan 3-1.
Swiss second division side Lausanne, trailing 3-1 at Sparta Prague after 23 minutes, hit back to draw 3-3 in the night's shock result while Italy's four teams all failed to win.
Palermo produced the worst performance of the quartet, losing 3-0 at home to CSKA Moscow, while Napoli were held to a goalless draw by visitors Liverpool.
Zenit St Petersburg, VfB Stuttgart, Porto and Sporting all won to maintain 100 percent records after three games along with CSKA.
Atletico Madrid's Diego Costa (centre) celebrates with teammates Filipe (left) and Sergio Aguero after scoring against Rosenborg
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