Ferguson, though, will be wary of another upset against Turkish opposition.
United lost at home to Besiktas last season in their first home European defeat for four years, although by then they had qualified for the knockout stages of the 2009-10 competition.
In 1996, Fenerbahce handed United their first home defeat ever in the Champions League/European Cup.
Bursaspor, however, are not in that class. They have lost their last six European games without scoring and have never scored in their five European away matches. In this campaign they lost 1-0 at Rangers and were thumped 4-0 at home by Valencia.
They also drew 2-2 at the weekend, against Karabukspor, and lead the Turkish league with 20 points from eight games.
Coach Ertugrul Saglam, whose Besiktas team was hammered 8-0 by Liverpool three years ago, travels to Old Trafford in a positive mood.
"United are going through a troubled time," he said. "There is no reason why we cannot return to Turkey with a surprise result."
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