Ajax Amsterdam striker Luis Suarez took his league tally for the season to 18 with a goal in the 3-0 home victory over NEC Nijmegen on Friday.
Jan Vertonghen set up Uruguayan Suarez seconds before the interval to open the scoring, with Siem de Jong and Mitchell Donald adding second-half goals.
Twente Enschede, in action on Saturday at home against NAC Breda, top the Dutch championship with 44 points after 16 matches, two more than PSV Eindhoven who host AZ Alkmaar on Saturday.
Ajax remain third with 38 points from 17 matches.